Yi Yi Ren (Seeds of Job's Tears)
Herb 24 of 28 in Herbs that Regulate Water and Drain Dampness
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Chinese Herb Actions
Tonifies the Spleen, Resolves Dampness
For dysuria, edema, leg qi, diarrhea, and damp febrile disorders due to Spleen deficiency leading to dampness.
- Clears Wind-Damp, Relieves Pain and Spasms
For stiff joints, muscle spasm and tendon pain due to wind damp painful obstruction.
- Clears Heat and Expels Pus
For lung and intestinal abscesses and postulated carbuncles due to heat. Also for any damp-heat disorder with a greasy tongue and digestion problem.
Chinese Herb Contraindications & Cautions
- None Noted
- None Noted
Chinese Herb Toxicity & Overdose
- None Noted
- Section not completed...
Chinese Herb Dosage
- 10-30 grams in decoction 12
- 9-30 grams in decoction 13
Chinese Herb Notes
- This herb is valued for its abilities to treat symptoms of Dampness while strengthening Spleen, much like Fu Ling. The main differences being Yi Yi Ren will clear heat and Fu Ling will calm the Heart.
Chinese Herb Clinical Studies & Research
- Many in-vivo and in-vitro studies indicate Yi Yi Ren is effective at inhibiting various types of cancer including pancreatic (1), lung (2, 3), and liver (4) cancer.
- 1. J Gastroenterol Hepatol. 2005 Jul; 20(7):1046-53.
Neutral lipid isolated from endosperm of Job's tears inhibits the growth of pancreatic cancer cells via apoptosis, G2/M arrest, and regulation of gene expression.
- 2. J Agric Food Chem. 2003 Jun 4; 51(12):3656-60
Antiproliferative and chemopreventive effects of adlay seed on lung cancer in vitro and in vivo.
- 3. J Agric Food Chem. 2003 Dec 3;51(25):7333-7.
Methanolic extract of adlay seed suppresses COX-2 expression of human lung cancer cells via inhibition of gene transcription.
- 4. Zhonghua Gan Zang Bing Za Zhi. 2002 Dec;10(6):452-4.
Interventional therapy combining Seed of Job's-tears with lipiodol for hepatoma-bearing rats
- 5. Planta Med. 1994 Aug;60(4):356-9.
Antitumor components isolated from the Chinese herbal medicine Coix lachryma-jobi.
- 6. Biotherapy. 1992;5(3):201-3.
Chinese medicine, Coix seeds increase peripheral cytotoxic T and NK cells.
This Herb Appears in the Following Formulas:
- San Ren Tang (Three Nut Decoction)
Category: Formulas that Clear Damp-Heat
- Shen Ling Bai Zhu San (Ginseng, Poria, and Atractylodes Macrocephala Powder)
Category: Formulas that Tonify the Qi
- Wei Jing Tang (Reed Decoction)
Category: Formulas that Clear Heat from the Organs
- Xiang Fu Xuan Fu Hua Tang (Cyperus and Inula Decoction)
Category: Formulas that Dry Dampness and Expel Phlegm
- Xuan Bi Tang (Disband Painful Obstruction Decoction)
Category: Formulas that Dispel Wind-Dampness