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Li Zhong Wan (Regulate the Middle Pill)

Previous Formula in CategoryNext Formula in Category Formula 5 of 10 in Formulas that Warm Interior Cold


  • Formulas that Warm the Channels and Disperse Cold


  • Middle Jiao (SP, ST) Yang deficiency with cold


  • Warms the Middle Jiao and dispels cold
  • Strengthens the Spleen and Stomach.


  • Watery diarrhea, undigested food in the stool, indigestion, nausea, vomiting, lack of thirst, abdominal pain that is relieved by warmth, poor appetite, and fatigue

Possible Tongue Appearance:

  • Pale tongue with white coat

Possible Pulse Patterns:

  • Deep, slow, and weak pulse

Western Uses:

  • Acute and Chronic Gastroenteritis
  • Gastro-Duodenal Ulcers
  • Irritable Bowel Syndrome
  • Gastrectasis
  • Gastroptosis
  • Chronic Colitis
  • Cholera
  • Vomiting
  • Anemia
  • Chronic Bronchitis
  • Oral Herpes
  • Functional Uterine Bleeding

Cautions, Contraindications, Herb Drug Interactions:

  • This formula is warm and drying it should not be used in cases with Yin deficiency and heat
  • Do not use in cases where external pathogens are present.

Preparation Notes:

  • Pills. Grind all herbs into an even powder and use honey to form into pills. Take in 9 gram doses 2-3 times a day.
  • In all but acute cases Dang Shen is substituted for Ren Shen.
  • This formula can also be prepared as a decoction.

Originally Appeared In:

  • On Cold Damage (Shang Han Lun)

Combined Channels of all herbs in this formula:

  • Lungs, Stomach, Spleen, Heart

Substances in this Formula (4 Total):

Gan Jiang (dry Rhizoma Zingiberis)
Gan Jiang (Dried Ginger Rhizome) 干姜
Qty: 9 grams
Chan: HT, LU, SP, ST
Prop: Spicy, Hot
Latin: dry Rhizoma Zingiberis
Cat: Herbs that Warm the Interior and Expel Cold
Ren Shen (Radix Ginseng)
Ren Shen (Ginseng Root) 人参
Qty: 9 grams
Chan: LU, SP
Prop: Sweet, Slightly Bitter, Slightly Warm
Latin: Radix Ginseng
Cat: Herbs that Tonify Qi
Bai Zhu (Rhizoma Atractylodis Macrocephalae)
Bai Zhu (White Atractylodes Rhizome) 白术
Qty: 9 grams
Chan: SP, ST
Prop: Bitter, Sweet, Warm
Latin: Rhizoma Atractylodis Macrocephalae
Cat: Herbs that Tonify Qi
Zhi Gan Cao (Radix Glycyrrhizae)
Zhi Gan Cao (Honey Fried Licorice Root) 炙甘草
Qty: 9 grams
Chan: All 12 Channels
Prop: Sweet, Warm
Latin: Radix Glycyrrhizae
Cat: Herbs that Tonify Qi
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